PRF for hair — the next-generation upgrade to PRP
PRF is PRP without the anticoagulant — a slower-release, higher-concentration growth factor gel. In London, it's overtaking PRP at leading clinics.
Dr. Theo Marwick
Hair Restoration Surgeon · Marylebone
In short
- Second-generation platelet concentrate — no anticoagulant.
- Slower release of growth factors over 7–14 days vs PRP's 24 hours.
- Higher platelet and leukocyte concentrations.
- London cost: £450–£800 per session; course of 3–4.
PRF (platelet-rich fibrin) is the natural evolution of PRP. Same blood-draw process, different spin protocol — no anticoagulant, so the platelets and fibrin form a matrix that releases growth factors over days instead of hours.
PRP vs PRF
- PRP: liquid, immediate release, requires anticoagulant
- PRF: gel/liquid matrix, sustained release, autologous fibrin scaffold
- PRF: higher platelet concentration per volume
- PRF: shorter processing time, no additives
Evidence and London use
Head-to-head trials show PRF non-inferior to PRP and, in some studies, superior for hair density and shaft diameter at 6 months. Adopted by leading London hair clinics over the past three years.
Protocol
Three sessions at 4-week intervals, maintenance every 4–6 months. Often combined with microneedling in the same session. Cost £450–£800 per treatment in London.
Frequently asked
Common questions
Is PRF better than PRP?+
Emerging evidence suggests yes for hair. Individual response varies.
Any downtime?+
Mild scalp swelling for 24 hours. Return to normal activity next day.
Can I combine with medical therapy?+
Yes — best results when layered with finasteride/minoxidil.
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